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Global variations in lung cancer incidence by histological subtype in 2020: a population-based study

Posted on by SGW Content
11
Feb

Tadeusz Dyba 1, Giorgia Randi 2, Freddie Bray 3, Carmen Martos 4, Francesco Giusti 4, Nicholas Nicholson 4, Anna Gavin 5, Manuela Flego 4, Luciana Neamtiu 4, Nadya Dimitrova 4, Raquel Negrão Carvalho 4, Jacques Ferlay 3, Manola Bettio 4
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PMID: 34560371 PMCID: PMC8568058 DOI: 10.1016/j.ejca.2021.07.039

Abstract

Introduction: Europe is an important focus for compiling accurate and up-to-date world cancer statistics owing to its large share of the world’s total cancer burden. This article presents incidence and mortality estimates for 25 major cancers across 40 individual countries within European areas and the European Union (EU-27) for the year 2020.

Methods: The estimated national incidence and mortality rates are based on statistical methodology previously applied and verified using the most recently collected incidence data from 151 population-based cancer registries, mortality data and 2020 population estimates.

Results: Estimates reveal 4 million new cases of cancer (excluding non-melanoma skin cancer) and 1.9 million cancer-related deaths. The most common cancers are: breast in women (530,000 cases), colorectum (520,000), lung (480,000) and prostate (470,000). These four cancers account for half the overall cancer burden in Europe. The most common causes of cancer deaths are: lung (380,000), colorectal (250,000), breast (140,000) and pancreatic (130,000) cancers. In EU-27, the estimated new cancer cases are approximately 1.4 million in males and 1.2 million in females, with over 710,000 estimated cancer deaths in males and 560,000 in females.

Conclusion: The 2020 estimates provide a basis for establishing priorities in cancer-control measures across Europe. The long-established role of cancer registries in cancer surveillance and the evaluation of cancer control measures remain fundamental in formulating and adapting national cancer plans and pan-European health policies. Given the estimates are built on recorded data prior to the onset of coronavirus disease 2019 (COVID-19), they do not take into account the impact of the pandemic.

Keywords: Cancer; Cancer registries; Estimation; Europe; Incidence; Mortality.

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Conflict of interest statement

Conflict of interest statement None declared.

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References

  1. Eurostat. Causes of Death statistics (hlth_cd_asdr2). Available at: https://ec.europa.eu/eurostat/web/main/data/database. [Last accessed 1 April 2021].
  2. Ferlay J., Colombet M., Soerjomataram I., Mathers C., Parkin D.M., Piñeros M. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int J Canc. 2019;144(8):1941–1953. doi: 10.1002/ijc.31937. Epub 2018 Dec 6. PMID: 30350310. – DOI – PubMed
  3. United Nations, Population division. World Population Prospects, the 2017 revision. https://esa.un.org/unpd/wpp/. [Accessed March 2021].
  4. Hofmarcher T., Lindgren P., Wilking N., Jönsson B. The cost of cancer in Europe 2018. Eur J Canc. 2020;129:41–49. doi: 10.1016/j.ejca.2020.01.011. Epub 2020 Feb 28. PMID: 32120274. – DOI – PubMed
  5. Jensen O.M., Estève J., Møller H., Renard H. Cancer in the European Community and its member states. Eur J Canc. 1990;26(11–12):1167–1256. doi: 10.1016/0277-5379(90)90278-2. Erratum in: Eur J Cancer 1991;27(12):1717. PMID: 2150000. – DOI – PubMed
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