All

Current and future burden of breast cancer: Global statistics for 2020 and 2040

Posted on by SGW Content
10
Feb

Melina Arnold 1, Eileen Morgan 2, Harriet Rumgay 1, Allini Mafra 1, Deependra Singh 1, Mathieu Laversanne 1, Jerome Vignat 1, Julie R Gralow 3, Fatima Cardoso 4, Sabine Siesling 5, Isabelle Soerjomataram 1
Affiliations Expand
PMID: 36084384 PMCID: PMC9465273 DOI: 10.1016/j.breast.2022.08.010

Abstract

Background: Breast cancer is the most commonly diagnosed cancer worldwide, and its burden has been rising over the past decades. In this article, we examine and describe the global burden of breast cancer in 2020 and predictions for the year 2040.

Methods: Estimates of new female breast cancer cases and deaths in 2020 were abstracted from the GLOBOCAN database. Age-standardized incidence and mortality rates were calculated per 100,000 females by country, world region, and level of human development. Predicted cases and deaths were computed based on global demographic projections for the year 2040.

Results: Over 2.3 million new cases and 685,000 deaths from breast cancer occurred in 2020. Large geographic variation across countries and world regions exists, with incidence rates ranging from <40 per 100,000 females in some Asian and African countries, to over 80 per 100,000 in Australia/New Zealand, Northern America, and parts of Europe. Smaller geographical variation was observed for mortality; however, transitioning countries continue to carry a disproportionate share of breast cancer deaths relative to transitioned countries. By 2040, the burden from breast cancer is predicted to increase to over 3 million new cases and 1 million deaths every year because of population growth and ageing alone.

Conclusion: Breast cancer is the most common cancer worldwide and continues to have a large impact on the global number of cancer deaths. Global efforts are needed to counteract its growing burden, especially in transitioning countries where incidence is rising rapidly, and mortality rates remain high.

Keywords: Breast cancer; Global; Incidence; Mortality; Prediction.

PubMed Disclaimer

Figures

Fig. 1

Fig. 2

Fig. 3

Fig. 4

Similar articles

  • Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN.

    Morgan E, Arnold M, Gini A, Lorenzoni V, Cabasag CJ, Laversanne M, Vignat J, Ferlay J, Murphy N, Bray F.Gut. 2023 Feb;72(2):338-344. doi: 10.1136/gutjnl-2022-327736. Epub 2022 Sep 8.PMID: 36604116
  • Global Burden of Cutaneous Melanoma in 2020 and Projections to 2040.

    Arnold M, Singh D, Laversanne M, Vignat J, Vaccarella S, Meheus F, Cust AE, de Vries E, Whiteman DC, Bray F.JAMA Dermatol. 2022 May 1;158(5):495-503. doi: 10.1001/jamadermatol.2022.0160.PMID: 35353115 Free PMC article.
  • Global burden of gynaecological cancers in 2022 and projections to 2050.

    Zhu B, Gu H, Mao Z, Beeraka NM, Zhao X, Anand MP, Zheng Y, Zhao R, Li S, Manogaran P, Fan R, Nikolenko VN, Wen H, Basappa B, Liu J.J Glob Health. 2024 Aug 16;14:04155. doi: 10.7189/jogh.14.04155.PMID: 39148469 Free PMC article.
  • Tuberculosis.

    Bloom BR, Atun R, Cohen T, Dye C, Fraser H, Gomez GB, Knight G, Murray M, Nardell E, Rubin E, Salomon J, Vassall A, Volchenkov G, White R, Wilson D, Yadav P.In: Holmes KK, Bertozzi S, Bloom BR, Jha P, editors. Major Infectious Diseases. 3rd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2017 Nov 3. Chapter 11.PMID: 30212088 Free Books & Documents. Review.
  • The Global Landscape of Esophageal Squamous Cell Carcinoma and Esophageal Adenocarcinoma Incidence and Mortality in 2020 and Projections to 2040: New Estimates From GLOBOCAN 2020.

    Morgan E, Soerjomataram I, Rumgay H, Coleman HG, Thrift AP, Vignat J, Laversanne M, Ferlay J, Arnold M.Gastroenterology. 2022 Sep;163(3):649-658.e2. doi: 10.1053/j.gastro.2022.05.054. Epub 2022 Jun 4.PMID: 35671803 Review.
See all similar articles

Cited by

  • Harnessing the potency of scorpion venom-derived proteins: applications in cancer therapy.

    El-Qassas J, Abd El-Atti M, El-Badri N.Bioresour Bioprocess. 2024 Oct 3;11(1):93. doi: 10.1186/s40643-024-00805-0.PMID: 39361208 Free PMC article. Review.
  • Anticancer, Immunomodulatory, and Phytochemical Screening of Carthamus oxyacantha M.Bieb Growing in the North of Iraq.

    Baban MM, Ahmad SA, Abu-Odeh AM, Baban M, Talib WH.Plants (Basel). 2023 Dec 22;13(1):42. doi: 10.3390/plants13010042.PMID: 38202350 Free PMC article.
  • Adipsin-dependent adipocyte maturation induces cancer cell invasion in breast cancer.

    Yoshida J, Hayashi T, Munetsuna E, Khaledian B, Sueishi F, Mizuno M, Maeda M, Watanabe T, Ushida K, Sugihara E, Imaizumi K, Kawada K, Asai N, Shimono Y.Sci Rep. 2024 Aug 9;14(1):18494. doi: 10.1038/s41598-024-69476-3.PMID: 39122742 Free PMC article.
  • The Role of Crohn Disease on Breast Cancer Incidence: A Clinical Analysis.

    Patel RK, Frankel L, Cardeiro M, Hansen W, Takabe K, Rashid OM.World J Oncol. 2023 Dec;14(6):457-463. doi: 10.14740/wjon1644. Epub 2023 Oct 21.PMID: 38022407 Free PMC article.
  • Trametinib boosts palbociclib’s efficacy in breast cancer via autophagy inhibition.

    Wu A, Yan J, Su T, Feng C, Long X, Pan Y, Ye R, Xia T, Long H, Wu J, Xiao X.Oncol Res. 2024 Jun 20;32(7):1197-1207. doi: 10.32604/or.2024.046139. eCollection 2024.PMID: 38948022 Free PMC article.
See all “Cited by” articles

References

    1. Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA A Cancer J Clin. 2021;71:209–249. – PubMed
    1. Heer E., Harper A., Escandor N., Sung H., McCormack V., Fidler-Benaoudia M.M. Global burden and trends in premenopausal and postmenopausal breast cancer: a population-based study. Lancet Global Health. 2020;8(8):e1027–e1037. – PubMed
    1. Anderson B.O., Ilbawi A.M., Fidarova E., Weiderpass E., Stevens L., Abdel-Wahab M., Mikkelsen B. The Global Breast Cancer Initiative: a strategic collaboration to strengthen health care for non-communicable diseases. Lancet Oncol. 2021;22(5):578–581. – PubMed
    1. Ferlay J., Colombet M., Soerjomataram I., Parkin D.M., Piñeros M., Znaor A., et al. Cancer statistics for the year 2020: an overview. Int J Cancer. 2021;149:778–789. – PubMed
    1. Global Cancer Observatory: Cancer Today [https://gco.iarc.fr/today/home].
SGW Content

Leave a Reply

Your email address will not be published. Required fields are marked *